Thursday, November 29, 2012

Abstract: Movement disorders and the eyes.

Twelve years ago, Current Opinion in Ophthalmology published a review titled "Neuro-ophthalmology of movement disorders". It includes no mention of corneal involvement from movement disorders, at least in the abstract.

Below is a review in the same journal, with an identical title, published November 2012. See for yourself the difference.

Dunno about you but I'll take any signs of progress I can find!


PURPOSE OF REVIEW:
Movement disorders commonly present with ocular features. The purpose of this review is to outline neuro-ophthalmologic findings that can help in diagnosis, treatment and determining prognosis in patients with movement disorders.
RECENT FINDINGS:
Common movement disorders with ophthalmic symptoms include extrapyramidal disorders such as Parkinson disease-associated dry eye, decreased blink rate, and vergence dysfunction, and progressive supranuclear palsy-related lid retraction, frequent square-wave jerks and supranuclear gaze palsy. Multisystem atrophy can present with gaze-evoked horizontal or positional downbeat nystagmus and impaired vestibulo-ocular reflex suppression. Genetic disorders such as Huntington disease produce increased saccadic latencies and impaired suppression of saccades to presented stimulus, whereas Wilson disease is associated with saccadic pursuits, increased antisaccade latencies and decreased pursuit gain. Whipple's disease can present with supranuclear gaze palsy and characteristic oculomasticatory myorrhythmia.
SUMMARY:
Movement disorders commonly present with ocular features. Knowledge of these ocular symptoms can assist the ophthalmologist in diagnosis and treatment of movement disorders.

Curr Opin Ophthalmol. 2012 Nov;23(6):491-6. doi: 10.1097/ICU.0b013e328358ba14.
Clark D, Eggenberger E.
Source
Michigan State University Department of Neurology and Ophthalmology, East Lansing, Michigan, USA.

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