Wednesday, April 10, 2013

Abstract: OCT in measuring tear film meniscus

Funny, I see abstracts about OCT in dry eye diagnosis pretty frequently. I dutifully post some of them. But unlike most other diagnostics covered so prolifically in the literature I hardly seem to hear about this one at all in 'real life'. Am I just out of touch? Who's using this?

Abstract Purpose: To compare tear meniscus height (TMH) and area (TMA) values obtained by optical coherence tomography (OCT) with the Schirmer test and tear-film break-up time (TBUT) values. Materials and methods: In this prospective cross-sectional study, the right eyes of 300 consecutive patients were studied. All patients underwent routine ophthalmologic examination. Schirmer and TBUT measurements were taken, and tear-film OCT images were obtained. Using OCT, the TMH (i.e. the line connecting the intersection of the meniscus with the cornea and eyelid) and cross-sectional TMA were calculated. Patients were divided into Groups 1 (Schirmer values ≤ 5mm) and 2 (Schirmer values > 5mm). Data were analyzed using SPSS 13.0 software. The Mann-Whitney U-test was used for the comparison of groups. Correlations between tear parameters were analyzed. Results: There were no significant differences in age, logMAR, or IOP values (p=0.480, 0.077 and 0.146, respectively) between the two groups. Mean TBUTs were 5.1±2.9 and 9.5±4.2s for Groups 1 and 2, respectively (p<0.001). Mean TMHs were 237.9±108.9 and 324.3±158.9μm for Groups 1 and 2, respectively (p<0.001). Mean TMAs were significantly lower in Group 1 compared to Group 2 (p<0.001; 0.027±0.028 versus 0.055±0.059mm2, respectively). Correlations between Schirmer values and TMH, and between Schirmer values and TMA, were significant (p=0.001 and < 0.001, respectively). Conclusions: OCT values were significantly lower in patients with Schirmer values of < 5mm. Tear meniscus measurements obtained by OCT are reliable for establishing a diagnosis of dry eye.

Curr Eye Res. 2013 Mar 14. [Epub ahead of print]
Altan-Yaycioglu R, Sizmaz S, Canan H, Coban-Karatas M.
Faculty of Medicine, Adana Teaching & Medical Research Center, Baskent University , 01250 Adana , Turkey.

1 comment:

Anonymous said...

While attempting contact lens fittings for complications of ocular surface disease and astigmatism, two optometrists have used OCT to determine adequate vault of the contact lens over the corneas.
In one instance, the OCT device had been purchased primarily for retina patients and contact lens patients had access for scleral lens fitting. In my case, neither doctor (different practices) used it for assessing dry eye.