Abstract Purpose: To compare tear meniscus height (TMH) and area (TMA) values obtained by optical coherence tomography (OCT) with the Schirmer test and tear-film break-up time (TBUT) values. Materials and methods: In this prospective cross-sectional study, the right eyes of 300 consecutive patients were studied. All patients underwent routine ophthalmologic examination. Schirmer and TBUT measurements were taken, and tear-film OCT images were obtained. Using OCT, the TMH (i.e. the line connecting the intersection of the meniscus with the cornea and eyelid) and cross-sectional TMA were calculated. Patients were divided into Groups 1 (Schirmer values ≤ 5 mm) and 2 (Schirmer values > 5 mm). Data were analyzed using SPSS 13.0 software. The Mann-Whitney U-test was used for the comparison of groups. Correlations between tear parameters were analyzed. Results: There were no significant differences in age, logMAR, or IOP values (p = 0.480, 0.077 and 0.146, respectively) between the two groups. Mean TBUTs were 5.1 ± 2.9 and 9.5 ± 4.2 s for Groups 1 and 2, respectively (p < 0.001). Mean TMHs were 237.9 ± 108.9 and 324.3 ± 158.9 μm for Groups 1 and 2, respectively (p < 0.001). Mean TMAs were significantly lower in Group 1 compared to Group 2 (p < 0.001; 0.027 ± 0.028 versus 0.055 ± 0.059 mm2, respectively). Correlations between Schirmer values and TMH, and between Schirmer values and TMA, were significant (p = 0.001 and < 0.001, respectively). Conclusions: OCT values were significantly lower in patients with Schirmer values of < 5 mm. Tear meniscus measurements obtained by OCT are reliable for establishing a diagnosis of dry eye.
Curr Eye Res. 2013 Mar 14. [Epub ahead of print]
Altan-Yaycioglu
R, Sizmaz S,
Canan H,
Coban-Karatas
M.
Source
Faculty of Medicine, Adana Teaching & Medical Research
Center, Baskent University , 01250 Adana , Turkey.
1 comment:
While attempting contact lens fittings for complications of ocular surface disease and astigmatism, two optometrists have used OCT to determine adequate vault of the contact lens over the corneas.
In one instance, the OCT device had been purchased primarily for retina patients and contact lens patients had access for scleral lens fitting. In my case, neither doctor (different practices) used it for assessing dry eye.
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